Čizmić, Mirta and Ljubas, Davor and Ćurković, Lidija and Škorić, Irena and Babić, Sandra (2017) Kinetics and degradation pathways of photolytic and photocatalytic oxidation of the anthelmintic drug praziquantel. = Kinetics and degradation pathways of photolytic and photocatalytic oxidation of the anthelmintic drug praziquantel. Journal of hazardous materials, 323. pp. 500-512. ISSN 0304-3894. Vrsta rada: ["eprint_fieldopt_article_type_article" not defined]. Kvartili JCR: Q1(2016). Točan broj autora: 5.
Full text not available from this repository.Abstract
In this study, an anthelmintic drug, praziquantel(PZQ), was degraded using the direct photolysis, photocatalysis, and oxidation processes including UV radiation, TiO2 film, and hydrogen peroxide. The photolytic degradation with predominant wavelengths of 185/254 nm (UV-C) proved to be more efficient with a half-life of 3.13 min compared to the radiation of 365 nm (UV-A) where the degradation did not occur. In order to enhance the rate of PZQ photolytic degradation, H2O2 was added, which resulted in two to three times higher degradation rates. In the photocatalytic degradation, TiO2 film was used as catalyst. The degradation was ten times faster in the photocatalytic experiments where UV-C light (k=0.2390 min-1) was used than in those with UV-A (k=0.0201 min-1). Comparing the results from all performed experiments it can be concluded that the UV-C/TiO2/H2O2 process yielded the highest degradation rate and complete degradation of PZQ was obtained in less than 7 minutes. The degradation of PZQ followed the first order kinetics in all the experiments. The photo degradation was inhibited in the presence of methanol. The degradation pathways and the structural formulae of five degradation products (m/z 273, 269, 189, 147, 132) were proposed based on the liquid chromatography tandem mass spectrometry analysis.
| Item Type: | Article (["eprint_fieldopt_article_type_article" not defined]) |
|---|---|
| Keywords (Croatian): | pharmaceuticals, praziquantel, photolysis and photocatalysis, titanium dioxide film, photodegradation pathway |
| Subjects: | NATURAL SCIENCES > Chemistry |
| Divisions: | 1000 Department of Materials > 1010 Chair of Materials and Tribology 500 Department of Energy, Power Engineering and Environment > 540 Chair of Water and Environmental Engineering |
| Indexed in Web of Science: | Yes |
| Indexed in Current Contents: | Yes |
| Quartiles: | Q1(2016) |
| Date Deposited: | 20 Sep 2016 09:33 |
| Last Modified: | 29 Aug 2017 12:59 |
| URI: | http://repozitorij.fsb.hr/id/eprint/6476 |
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